Cerebral Blood Flow Physiology and Metabolism
نویسندگان
چکیده
The brain comprises only 2% of total body weight; however, under normal conditions, it receives 15–20% of the cardiac output and accounts for 20% of total body oxygen consumption. Because energy reserves within the brain are negligible, adequate blood flow is essential for the provision of a continuous supply of energy-producing substrates and for the removal of the byproducts of cellular metabolism.
منابع مشابه
CEREBRAL BLOOD FLOW REGULATION IN ANESTHETIZED MORPHINE DEPENDENT RATS: THE ROLE OF THE ADENOSINE SYSTEM
Adenosine has many of the characteristics of a regulator of cerebral blood flow and adenosine receptors change in morphine dependency. In this study the changes in adenosine receptors' responsiveness of pial vessels in the hind limb area of the sensory cortex were evaluated in morphine dependent rats (MDR) using the laser Doppler flowmetry technique. Adult male Sprague Dawley rats (250-350 ...
متن کاملBone biochemical marker response to a plyometric exercise session with and without blood flow restriction in inactive adolescent females
Background and Aims: Physical activity and blood flow restriction (BFR) training can affect bone metabolism. This study aimed to investigate the effect of a plyometric exercise session with and without blood flow restriction on bone metabolism markers, such as bone alkaline phosphatase (BALP) and C-terminal telopeptide of type 1collagen (CTX), as the markers of bone formation and destruction, ...
متن کاملThe Effect of Hurdling Performance on The Adaptive Profile of Cerebral Blood Flow in Vestibular Irritation
Background: The reactions of the whole organism that occur under the action of accelerations of rectilinear and rotational motion are factors that have a systemic effect on the cerebral blood flow. The use of hurdling performance in the structure of human physical activity can have a significant impact on the tone of the brain vessels, their elasticity and venous outflow in the development of f...
متن کاملInhibition of nitric oxide synthase activity improves focal cerebral damage induced by cerebral ischemia/reperfusion in normotensive rats
Introduction: Nitric oxide seems to play a dual role in ischemia/reperfusion injury. Few studies have investigated whether it exacerbates or improves brain edema. In the present study, we inhibited the activity of nitric oxide synthase by L-NAME and evaluated the cerebral infarct volume, tissue swelling and brain edema, alongside the measurement of blood flow of the ischemic region. Methods...
متن کاملOptical coherence tomography for the quantitative study of cerebrovascular physiology.
Doppler optical coherence tomography (DOCT) and OCT angiography are novel methods to investigate cerebrovascular physiology. In the rodent cortex, DOCT flow displays features characteristic of cerebral blood flow, including conservation along nonbranching vascular segments and at branch points. Moreover, DOCT flow values correlate with hydrogen clearance flow values when both are measured simul...
متن کاملMild exercise along with limb blood-flow restriction modulates the electrocardiogram, angiotensin, and apelin receptors of the heart in aging rats
Objective(s): Considering the lack of information, the effects of mild endurance exercise plus blood flow restriction (BFR) on electrocardiographic parameters, hypertrophy index, and expression of angiotensin II receptors type 1 (AT1R) and type 2 (AT2R) and apelin receptor (APJ) were assessed in hearts of old male rats.Materials and Methods: Animal were grouped as control (CTL), Sham (Sh), lowe...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2009